human GRB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GRB2.
shAAV-210489
AAV-h-GRB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GRB2 (growth factor receptor bound protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Description (Vector)
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
2885
Gene Name (Vector)
growth factor receptor bound protein 2
Gene Symbol
GRB2
HGNC ID
HGNC:4566
ORF Size (aa)
654
ORF Size (bp)
654 bp
RefSeq ID
NM_002086
RefSeq Synonyms
NM_203506, NM_002086, BC000631,
Species
human
UniGene ID
Hs.444356
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.