human GRAP2 shRNA silencing AAV

Name 
AAV-h-GRAP2-shRNA
Cat No 
shAAV-210483
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GRAP2.

shAAV-210483
AAV-h-GRAP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GRAP2 (GRB2-related adaptor protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GADS; GRAP-2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38
Description (Vector)
GRAP2 encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
Gene ID
9402
Gene Name (Vector)
GRB2-related adaptor protein 2
Gene Symbol
GRAP2
HGNC ID
HGNC:4563
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_004810
RefSeq Synonyms
NM_004810, NM_001291828, NM_001291826, NM_001291825, NM_001291824, BC026002, BC025692,
Species
human
UniGene ID
Hs.517499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.