human GPX3 shRNA silencing AAV

Name 
AAV-h-GPX3-shRNA
Cat No 
shAAV-210460
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GPX3.

shAAV-210460
AAV-h-GPX3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GPX3 (glutathione peroxidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPx-P; GSHPx-3; GSHPx-P
Description (Vector)
GPX3 product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
Gene ID
2878
Gene Name (Vector)
glutathione peroxidase 3
Gene Symbol
GPX3
HGNC ID
HGNC:4555
ORF Size (aa)
681
ORF Size (bp)
681 bp
RefSeq ID
NM_002084
RefSeq Synonyms
NM_002084, NM_001329790, BC050378, BC035841, BC013601,
Species
human
UniGene ID
Hs.386793

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.