human GPR50 shRNA silencing AAV

Name
AAV-h-GPR50-shRNA

Cat No
shAAV-210361

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GPR50.

shAAV-210361

AAV-h-GPR50-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GPR50 (G protein-coupled receptor 50). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H9; Mel1c

Description (Vector)

GPR50 product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.

Gene ID

9248

Gene Name (Vector)

G protein-coupled receptor 50

Gene Symbol

GPR50

HGNC ID

HGNC:4506

ORF Size (aa)

1854

ORF Size (bp)

1854 bp

RefSeq ID

NM_004224

RefSeq Synonyms

NM_004224, BC105684, BC105683, BC103696,

Species

human

UniGene ID

Hs.567390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.