human GPKOW shRNA silencing AAV

Name
AAV-h-GPKOW-shRNA

Cat No
shAAV-210236

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GPKOW.

shAAV-210236

AAV-h-GPKOW-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GPKOW (G-patch domain and KOW motifs). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

G patch domain and KOW motifs-containing protein; GPATC5; G-patch domain and KOW motifs-containing protein; G-patch domain-containing protein 5; GPATCH5; protein MOS2 homolog; Protein T54; Spp2; T54

Description (eCommerce)

GPKOW is a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. GPKOW interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosom [taken from NCBI Entrez Gene (Gene ID: 27238)].

Description (Vector)

GPKOW encodes a protein with G-patch and KOW domains which are involved in RNA binding. The encoded protein may be orthologous to the Arabidopsis protein, modifier of snc 1, 2, which contains the same domains and is required for innate resistance to some pathogens (PMID: 16271871).

Gene ID

27238

Gene Name (eCommerce)

G-patch domain and KOW motifs

Gene Name (Vector)

G-patch domain and KOW motifs

Gene Symbol

GPKOW

HGNC ID

HGNC:30677

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1431

ORF Size (bp)

1431 bp

Protein Name (eCommerce)

G patch domain and KOW motifs-containing protein

RefSeq ID

NM_015698

RefSeq Synonyms

NM_015698, BC003148, BC000397,

Research Areas

Cell Biology,Translational Control

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

GPKOW is a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. GPKOW interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosom [taken from NCBI Entrez Gene (Gene ID: 27238)].

UniGene ID

Hs.503666

UniProt ID (eCommerce)

Q92917

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.