human GPD1L shRNA silencing AAV

Name
AAV-h-GPD1L-shRNA

Cat No
shAAV-210224

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GPD1L.

shAAV-210224

AAV-h-GPD1L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GPD1L (glycerol-3-phosphate dehydrogenase 1-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GPD1-L

Description (Vector)

GPD1L catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).

Gene ID

23171

Gene Name (Vector)

glycerol-3-phosphate dehydrogenase 1-like

Gene Symbol

GPD1L

HGNC ID

HGNC:28956

ORF Size (aa)

1056

ORF Size (bp)

1056 bp

RefSeq ID

NM_015141

RefSeq Synonyms

NM_015141, BC028726,

Species

human

UniGene ID

Hs.82432

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.