human GNG5 shRNA silencing AAV

Name 
AAV-h-GNG5-shRNA
Cat No 
shAAV-210117
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GNG5.

shAAV-210117
AAV-h-GNG5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GNG5 (G protein subunit gamma 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 (PubMed 3113327); summary by Ahmad et al., 1995) (PubMed 7606925).(supplied by OMIM, Nov 2010)
Gene ID
2787
Gene Name (Vector)
G protein subunit gamma 5
Gene Symbol
GNG5
HGNC ID
HGNC:4408
ORF Size (aa)
207
RefSeq ID
NM_005274
RefSeq Synonyms
NM_005274, BC003563,
Species
human
UniGene ID
Hs.645427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.