human GLS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GLS.
shAAV-210002
AAV-h-GLS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GLS (glutaminase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AAD20; GAC; GAM; GLS1; KGA
Description (Vector)
GLS encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
Gene ID
2744
Gene Name (Vector)
glutaminase
Gene Symbol
GLS
HGNC ID
HGNC:4331
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
RefSeq ID
NM_014905
RefSeq Synonyms
NM_014905, NM_001256310, BC038507,
Species
human
UniGene ID
Hs.116448
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.