human GLRA1 shRNA silencing AAV

Name
AAV-h-GLRA1-shRNA

Cat No
shAAV-209989

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GLRA1.

shAAV-209989

AAV-h-GLRA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GLRA1 (glycine receptor alpha 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HKPX1; STHE

Description (Vector)

GLRA1 is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

2741

Gene Name (Vector)

glycine receptor alpha 1

Gene Symbol

GLRA1

HGNC ID

HGNC:4326

ORF Size (aa)

1350

ORF Size (bp)

1350 bp

RefSeq ID

NM_000171

RefSeq Synonyms

NM_001292000, NM_001146040, NM_000171, BC114967, BC114947, BC074980,

Species

human

UniGene ID

Hs.121490

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.