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human GK shRNA silencing AAV

Name 
AAV-h-GK-shRNA
Cat No 
shAAV-209946
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GK.

shAAV-209946
AAV-h-GK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GK (glycerol kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GK1; GKD
Description (Vector)
GK belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
2710
Gene Name (Vector)
glycerol kinase
Gene Symbol
GK
HGNC ID
HGNC:4289
ORF Size (aa)
1575
ORF Size (bp)
1575 bp
RefSeq ID
NM_000167
RefSeq Synonyms
NM_203391, NM_001205019, NM_001128127, NM_000167, BC071595, BC042421, BC037549,
Species
human
UniGene ID
Hs.1466

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.