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human GGTLC1 shRNA silencing AAV

Name 
AAV-h-GGTLC1-shRNA
Cat No 
shAAV-209855
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GGTLC1.

shAAV-209855
AAV-h-GGTLC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GGTLC1 (gamma-glutamyltransferase light chain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ831C21.1; dJ831C21.2; GGTL6; GGTLA3; GGTLA4
Description (Vector)
GGTLC1 encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
92086
Gene Name (Vector)
gamma-glutamyltransferase light chain 1
Gene Symbol
GGTLC1
HGNC ID
HGNC:16437
ORF Size (aa)
678
ORF Size (bp)
678 bp
RefSeq ID
NM_178312
RefSeq Synonyms
NM_178312, NM_178311, BC040904,
Species
human
UniGene ID
Hs.355394

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.