human CERS1 shRNA silencing AAV

Name 
AAV-h-CERS1-shRNA
Cat No 
shAAV-209772
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CERS1.

shAAV-209772
AAV-h-CERS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CERS1 (ceramide synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EPM8; LAG1; LASS1; UOG1
Description (Vector)
CERS1 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.
Gene ID
10715
Gene Name (Vector)
ceramide synthase 1
Gene Symbol
CERS1
HGNC ID
HGNC:14253
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_021267
RefSeq Synonyms
NM_198207, NM_021267, NM_001290265, BC084582,
Species
human
UniGene ID
Hs.412355

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.