human GDAP1L1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GDAP1L1.
shAAV-209767
AAV-h-GDAP1L1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GDAP1L1 (ganglioside induced differentiation associated protein 1 like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dJ881L22.1; dJ995J12.1.1
Description (Vector)
The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
Gene ID
78997
Gene Name (Vector)
ganglioside induced differentiation associated protein 1 like 1
Gene Symbol
GDAP1L1
HGNC ID
HGNC:4213
ORF Size (aa)
1104
RefSeq ID
NM_024034
RefSeq Synonyms
NM_024034, NM_001256740, NM_001256739, NM_001256738, NM_001256737, BC009014, BC000199,
Species
human
UniGene ID
Hs.517059
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.