human GCDH shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GCDH.
shAAV-209733
AAV-h-GCDH-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GCDH (glutaryl-CoA dehydrogenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACAD5; GCD
Description (Vector)
GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
2639
Gene Name (Vector)
glutaryl-CoA dehydrogenase
Gene Symbol
GCDH
HGNC ID
HGNC:4189
ORF Size (aa)
1317
ORF Size (bp)
1317 bp
RefSeq ID
NM_013976
RefSeq Synonyms
NM_013976, NM_000159, BC002579,
Species
human
UniGene ID
Hs.532699
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.