human GBP2 shRNA silencing AAV

Name
AAV-h-GBP2-shRNA

Cat No
shAAV-209716

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GBP2.

shAAV-209716

AAV-h-GBP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GBP2 (guanylate binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.

Gene ID

2634

Gene Name (Vector)

guanylate binding protein 2

Gene Symbol

GBP2

HGNC ID

HGNC:4183

ORF Size (aa)

1776

ORF Size (bp)

1776 bp

RefSeq ID

NM_004120

RefSeq Synonyms

NM_004120, BC073163, BC022272,

Species

human

UniGene ID

Hs.386567

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.