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human GANAB shRNA silencing AAV

Name 
AAV-h-GANAB-shRNA
Cat No 
shAAV-209629
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GANAB.

shAAV-209629
AAV-h-GANAB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GANAB (glucosidase II alpha subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alpha-glucosidase 2; G2AN; GIIA; Glucosidase II subunit alpha; GLUII; neutral alpha-glucosidase AB; PKD3
Description (eCommerce)
GANAB/Glucosidase II Subunit alpha sequentially cleaves the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14697].
Gene ID
23193
Gene Name (eCommerce)
glucosidase II alpha subunit
Gene Name (Vector)
glucosidase II alpha subunit
Gene Symbol
GANAB
HGNC ID
HGNC:4138
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2544
ORF Size (bp)
2544 bp
Protein Name (eCommerce)
Neutral alpha-glucosidase AB
RefSeq ID
NM_198334
RefSeq Synonyms
NM_198335, NM_198334, NM_001329225, NM_001329224, NM_001329223, NM_001329222, NM_001278194, NM_001278193, NM_001278192, BC065266,
Research Areas
Golgi Apparatus,Metabolism/Metabolic Process,Protein Folding,Signal Transduction,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
GANAB/Glucosidase II Subunit alpha sequentially cleaves the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14697].
UniGene ID
Hs.595071
UniProt ID (eCommerce)
Q14697

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.