human GALNT9 shRNA silencing AAV

Name
AAV-h-GALNT9-shRNA

Cat No
shAAV-209606

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GALNT9.

shAAV-209606

AAV-h-GALNT9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GALNT9 (polypeptide N-acetylgalactosaminyltransferase 9). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GALNAC-T9; GALNACT9

Description (Vector)

GALNT9 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. GALNT9 is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

50614

Gene Name (Vector)

polypeptide N-acetylgalactosaminyltransferase 9

Gene Symbol

GALNT9

HGNC ID

HGNC:4131

ORF Size (aa)

1422

ORF Size (bp)

1422 bp

RefSeq ID

NM_021808

RefSeq Synonyms

NM_021808, NM_001122636, BC171844, BC157845, BC093819,

Species

human

UniGene ID

Hs.658249

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.