human GALNAC4S-6ST shRNA silencing AAV

Name
AAV-h-GALNAC4S-6ST-shRNA

Cat No
shAAV-209580

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CHST15.

shAAV-209580

AAV-h-GALNAC4S-6ST-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHST15 (carbohydrate sulfotransferase 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BRAG; GALNAC4S-6ST

Description (Vector)

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

51363

Gene Name (Vector)

carbohydrate sulfotransferase 15

Gene Symbol

CHST15

HGNC ID

HGNC:18137

ORF Size (aa)

1515

ORF Size (bp)

1515 bp

RefSeq ID

NM_015892

RefSeq Synonyms

NM_015892, NM_014863, NM_001270765, NM_001270764, BC075813, BC050540, BC027908,

Species

human

UniGene ID

Hs.287537

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.