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human GABRG2 shRNA silencing AAV

Name 
AAV-h-GABRG2-shRNA
Cat No 
shAAV-209527
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GABRG2.

shAAV-209527
AAV-h-GABRG2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GABRG2 (gamma-aminobutyric acid type A receptor gamma2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAE2; ECA2; GEFSP3
Description (Vector)
GABRG2 encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
Gene ID
2566
Gene Name (Vector)
gamma-aminobutyric acid type A receptor gamma2 subunit
Gene Symbol
GABRG2
HGNC ID
HGNC:4087
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
RefSeq ID
NM_000816
RefSeq Synonyms
NM_198904, NM_198903, NM_000816, BC074795, BC069348, BC059389,
Species
human
UniGene ID
Hs.7195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.