human GABRA6 shRNA silencing AAV

Name 
AAV-h-GABRA6-shRNA
Cat No 
shAAV-209512
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GABRA6.

shAAV-209512
AAV-h-GABRA6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GABRA6 (gamma-aminobutyric acid type A receptor alpha6 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Gene ID
2559
Gene Name (Vector)
gamma-aminobutyric acid type A receptor alpha6 subunit
Gene Symbol
GABRA6
HGNC ID
HGNC:4080
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_000811
RefSeq Synonyms
NM_000811, BC099641, BC099640, BC096242, BC096241,
Species
human
UniGene ID
Hs.90791

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.