human GABRA2 shRNA silencing AAV

Name 
AAV-h-GABRA2-shRNA
Cat No 
shAAV-209507
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GABRA2.

shAAV-209507
AAV-h-GABRA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GABRA2 (gamma-aminobutyric acid type A receptor alpha2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
2555
Gene Name (Vector)
gamma-aminobutyric acid type A receptor alpha2 subunit
Gene Symbol
GABRA2
HGNC ID
HGNC:4076
ORF Size (aa)
1104
ORF Size (bp)
1104 bp
RefSeq ID
NM_000807
RefSeq Synonyms
NM_001330690, NM_001286827, NM_001114175, NM_000807, BC022488,
Species
human
UniGene ID
Hs.116250

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.