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human GABBR2 shRNA silencing AAV

Name 
AAV-h-GABBR2-shRNA
Cat No 
shAAV-209500
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GABBR2.

shAAV-209500
AAV-h-GABBR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GABBR2 (gamma-aminobutyric acid type B receptor subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GABABR2; GPR51; GPRC3B; HG20; HRIHFB2099
Description (Vector)
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Gene ID
9568
Gene Name (Vector)
gamma-aminobutyric acid type B receptor subunit 2
Gene Symbol
GABBR2
HGNC ID
HGNC:4507
ORF Size (aa)
2652
ORF Size (bp)
2652 bp
RefSeq ID
NM_005458
RefSeq Synonyms
NM_005458, BC035071,
Species
human
UniGene ID
Hs.198612

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.