human FYTTD1 shRNA silencing AAV

Name
AAV-h-FYTTD1-shRNA

Cat No
shAAV-209454

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FYTTD1.

shAAV-209454

AAV-h-FYTTD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FYTTD1 (forty-two-three domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

forty-two-three domain-containing protein 1; protein 40-2-3; UAP56-interacting factor; UIF

Description (eCommerce)

UAP56-interacting factor (UIF) is a factor required for mRNA export from the nucleus to the cytoplasm. UIF acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. UIF associates with spliced and unspliced mRNAs simultaneously with THOC4 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96QD9].

Gene ID

84248

Gene Name (eCommerce)

forty-two-three domain containing 1

Gene Name (Vector)

forty-two-three domain containing 1

Gene Symbol

FYTTD1

HGNC ID

HGNC:25407

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

957

ORF Size (bp)

957 bp

Protein Name (eCommerce)

UAP56-interacting factor

RefSeq ID

NM_032288

RefSeq Synonyms

NM_032288, NM_001011537, BC039734, BC035006,

Research Areas

mRNA Binding,mRNA transport,RNA Binding,RNA Processing,RNA Transport,Transport

Research Areas (Faceted)

genetics,transcription_translation,cell_biology

Species

human

Target Sentence

UAP56-interacting factor (UIF) is a factor required for mRNA export from the nucleus to the cytoplasm. UIF acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. UIF associates with spliced and unspliced mRNAs simultaneously with THOC4 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96QD9].

UniGene ID

Hs.277533

UniProt ID (eCommerce)

Q96QD9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.