human FXYD4 shRNA silencing AAV

Name
AAV-h-FXYD4-shRNA

Cat No
shAAV-209446

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FXYD4.

shAAV-209446

AAV-h-FXYD4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FXYD4 (FXYD domain containing ion transport regulator 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CHIF

Description (Vector)

FXYD4 encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na,K-ATPase, as has FXYD2, also known as the gamma subunit of the Na,K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.

Gene ID

53828

Gene Name (Vector)

FXYD domain containing ion transport regulator 4

Gene Symbol

FXYD4

HGNC ID

HGNC:4028

ORF Size (aa)

270

RefSeq ID

NM_173160

RefSeq Synonyms

NM_173160, NM_001184963, BC054876,

Species

human

UniGene ID

Hs.130497

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.