human FXN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FXN.
shAAV-209435
AAV-h-FXN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FXN (frataxin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CyaY; FA; FARR; FRDA; X25
Description (Vector)
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Gene ID
2395
Gene Name (Vector)
frataxin
Gene Symbol
FXN
HGNC ID
HGNC:3951
ORF Size (aa)
633
RefSeq ID
NM_000144
RefSeq Synonyms
NM_181425, NM_001161706, NM_000144, BC048097, BC023633,
Species
human
UniGene ID
Hs.29978
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.