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human FREM2 shRNA silencing AAV

Name 
AAV-h-FREM2-shRNA
Cat No 
shAAV-209307
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FREM2.

shAAV-209307
AAV-h-FREM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FREM2 (FRAS1 related extracellular matrix protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
FREM2 encodes a membrane protein that belongs to the FRAS1 family. This extracellular matrix protein is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes. Mutations in this gene are associated with Fraser syndrome.
Gene ID
341640
Gene Name (Vector)
FRAS1 related extracellular matrix protein 2
Gene Symbol
FREM2
HGNC ID
HGNC:25396
ORF Size (aa)
9510
ORF Size (bp)
9510 bp
RefSeq ID
NM_207361
RefSeq Synonyms
NM_207361, BC172230,
Species
human
UniGene ID
Hs.253994

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.