human FOXA1 shRNA silencing AAV

Name
AAV-h-FOXA1-shRNA

Cat No
shAAV-209225

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FOXA1.

shAAV-209225

AAV-h-FOXA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FOXA1 (forkhead box A1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

forkhead box protein A1; hepatocyte nuclear factor 3-alpha; HNF3A; HNF-3A; HNF-3-alpha; TCF3A; TCF-3A; transcription factor 3A

Description (eCommerce)

Forkhead box protein A1 (FOXA1) is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver [taken from NCBI Entrez Gene (Gene ID: 3169)].

Description (Vector)

FOXA1 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

Gene ID

3169

Gene Name (eCommerce)

forkhead box A1

Gene Name (Vector)

forkhead box A1

Gene Symbol

FOXA1

HGNC ID

HGNC:5021

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1419

ORF Size (bp)

1419 bp

Protein Name (eCommerce)

Hepatocyte nuclear factor 3-alpha

RefSeq ID

NM_004496

RefSeq Synonyms

NM_004496, BC033890,

Research Areas

Cancer,Cell Cycle,Estrogen Signaling,Neurobiology,Neurodevelopment,Prostate Cancer,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cancer,cell_biology,cell_cycle,developmental_biology,genetics,transcription_translation,neurobiology,signal_transduction

Species

human

Target Sentence

Forkhead box protein A1 (FOXA1) is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver [taken from NCBI Entrez Gene (Gene ID: 3169)].

UniGene ID

Hs.163484

UniProt ID (eCommerce)

P55317

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.