human FOLR1 shRNA silencing AAV

Name
AAV-h-FOLR1-shRNA

Cat No
shAAV-209217

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FOLR1.

shAAV-209217

AAV-h-FOLR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FOLR1 (folate receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FBP; FOLR

Description (Vector)

FOLR1 is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Gene ID

2348

Gene Name (Vector)

folate receptor 1

Gene Symbol

FOLR1

HGNC ID

HGNC:3791

ORF Size (aa)

774

ORF Size (bp)

774 bp

RefSeq ID

NM_000802

RefSeq Synonyms

NM_016729, NM_016725, NM_016724, NM_000802, BC002947,

Species

human

UniGene ID

Hs.73769

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.