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human FN3KRP shRNA silencing AAV

Name 
AAV-h-FN3KRP-shRNA
Cat No 
shAAV-209192
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FN3KRP.

shAAV-209192
AAV-h-FN3KRP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FN3KRP (fructosamine 3 kinase related protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FN3KL
Description (Vector)
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
Gene ID
79672
Gene Name (Vector)
fructosamine 3 kinase related protein
Gene Symbol
FN3KRP
HGNC ID
HGNC:25700
ORF Size (aa)
930
ORF Size (bp)
930 bp
RefSeq ID
NM_024619
RefSeq Synonyms
NM_024619, BC014408, BC007611,
Species
human
UniGene ID
Hs.31431

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.