human FGF13 shRNA silencing AAV

Name
AAV-h-FGF13-shRNA

Cat No
shAAV-208949

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FGF13.

shAAV-208949

AAV-h-FGF13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FGF13 (fibroblast growth factor 13). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FGF-13; FGF2; FHF-2; FHF2

Description (Vector)

FGF13 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.

Gene ID

2258

Gene Name (Vector)

fibroblast growth factor 13

Gene Symbol

FGF13

HGNC ID

HGNC:3670

ORF Size (aa)

738

ORF Size (bp)

738 bp

RefSeq ID

NM_004114

RefSeq Synonyms

NM_033642, NM_004114, NM_001139502, NM_001139501, NM_001139500, NM_001139498, BC034340, BC012347,

Species

human

UniGene ID

Hs.711551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.