human FCGRT shRNA silencing AAV

Name 
AAV-h-FCGRT-shRNA
Cat No 
shAAV-208866
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FCGRT.

shAAV-208866
AAV-h-FCGRT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FCGRT (Fc fragment of IgG receptor and transporter). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alpha-chain; FCRN
Description (Vector)
FCGRT encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
Gene ID
2217
Gene Name (Vector)
Fc fragment of IgG receptor and transporter
Gene Symbol
FCGRT
HGNC ID
HGNC:3621
ORF Size (aa)
1098
ORF Size (bp)
1098 bp
RefSeq ID
NM_004107
RefSeq Synonyms
NM_004107, NM_001136019, BC008734,
Species
human
UniGene ID
Hs.111903

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.