human FBXO5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FBXO5.
shAAV-208823
AAV-h-FBXO5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FBXO5 (F-box protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EMI1; FBX5; Fbxo31
Description (Vector)
FBXO5 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
26271
Gene Name (Vector)
F-box protein 5
Gene Symbol
FBXO5
HGNC ID
HGNC:13584
ORF Size (aa)
1344
ORF Size (bp)
1344 bp
RefSeq ID
NM_012177
RefSeq Synonyms
NM_012177, NM_001142522, BC018905,
Species
human
UniGene ID
Hs.520506
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.