human FBXO46 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FBXO46.
shAAV-208819
AAV-h-FBXO46-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FBXO46 (F-box protein 46). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
20D7-FC4; Fbx46; FBXO34L
Description (Vector)
Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)
Gene ID
23403
Gene Name (Vector)
F-box protein 46
Gene Symbol
FBXO46
HGNC ID
HGNC:25069
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
RefSeq ID
NM_001080469
RefSeq Synonyms
NM_001329634, NM_001329633, NM_001329632, NM_001080469, BC021978,
Species
human
UniGene ID
Hs.128702
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.