human FAM38B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIEZO2.
shAAV-208552
AAV-h-FAM38B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIEZO2 (piezo type mechanosensitive ion channel component 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C18orf30; C18orf58; DA3; DA5; DAIPT; FAM38B; FAM38B2; HsT748; HsT771; MWKS
Description (Vector)
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 (PubMed 20813920)).(supplied by OMIM, Nov 2010)
Gene ID
63895
Gene Name (Vector)
piezo type mechanosensitive ion channel component 2
Gene Symbol
PIEZO2
HGNC ID
HGNC:26270
ORF Size (aa)
1632
ORF Size (bp)
1632 bp
RefSeq ID
NM_022068
RefSeq Synonyms
NM_022068, BC148379,
Species
human
UniGene ID
Hs.585839
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.