human FADS1 shRNA silencing AAV

Name
AAV-h-FADS1-shRNA

Cat No
shAAV-208258

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human FADS1.

shAAV-208258

AAV-h-FADS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FADS1 (fatty acid desaturase 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

D5D; FADS6; FADSD5; LLCDL1; TU12

Description (Vector)

FADS1 is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

Gene ID

3992

Gene Name (Vector)

fatty acid desaturase 1

Gene Symbol

FADS1

HGNC ID

HGNC:3574

ORF Size (aa)

1335

ORF Size (bp)

1335 bp

RefSeq ID

NM_013402

RefSeq Synonyms

NM_013402, BC007846,

Species

human

UniGene ID

Hs.503546

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.