human EXOSC8 shRNA silencing AAV

Name 
AAV-h-EXOSC8-shRNA
Cat No 
shAAV-208195
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EXOSC8.

shAAV-208195
AAV-h-EXOSC8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EXOSC8 (exosome component 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA421P11.3; CIP3; EAP2; OIP2; p9; PCH1C; RRP43; Rrp43p
Description (Vector)
EXOSC8 encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
Gene ID
11340
Gene Name (Vector)
exosome component 8
Gene Symbol
EXOSC8
HGNC ID
HGNC:17035
ORF Size (aa)
831
ORF Size (bp)
831 bp
RefSeq ID
NM_181503
RefSeq Synonyms
NM_181503, BC020773,
Species
human
UniGene ID
Hs.294041

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.