human EVC2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EVC2.
shAAV-208153
AAV-h-EVC2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EVC2 (EvC ciliary complex subunit 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LBN; WAD
Description (Vector)
EVC2 encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants.
Gene ID
132884
Gene Name (Vector)
EvC ciliary complex subunit 2
Gene Symbol
EVC2
HGNC ID
HGNC:19747
ORF Size (aa)
3684
ORF Size (bp)
3684 bp
RefSeq ID
NM_147127
RefSeq Synonyms
NM_147127, NM_001166136, BC111455,
Species
human
UniGene ID
Hs.87306
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.