human EMCN shRNA silencing AAV

Name
AAV-h-EMCN-shRNA

Cat No
shAAV-207870

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EMCN.

shAAV-207870

AAV-h-EMCN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EMCN (endomucin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EMCN2; MUC14

Description (Vector)

EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 (PubMed 11418125)).(supplied by OMIM, Mar 2008)

Gene ID

51705

Gene Name (Vector)

endomucin

Gene Symbol

EMCN

HGNC ID

HGNC:16041

ORF Size (aa)

537

RefSeq ID

NM_016242

RefSeq Synonyms

NM_016242, NM_001159694, BC017781,

Species

human

UniGene ID

Hs.152913

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.