human ELOVL4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ELOVL4.
shAAV-207860
AAV-h-ELOVL4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ELOVL4 (ELOVL fatty acid elongase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADMD; CT118; ISQMR; SCA34; STGD2; STGD3
Description (Vector)
ELOVL4 encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
Gene ID
6785
Gene Name (Vector)
ELOVL fatty acid elongase 4
Gene Symbol
ELOVL4
HGNC ID
HGNC:14415
ORF Size (aa)
945
ORF Size (bp)
945 bp
RefSeq ID
NM_022726
RefSeq Synonyms
NM_022726, BC038506,
Species
human
UniGene ID
Hs.101915
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.