human EFNA2 shRNA silencing AAV

Name
AAV-h-EFNA2-shRNA

Cat No
shAAV-207633

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human EFNA2.

shAAV-207633

AAV-h-EFNA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EFNA2 (ephrin A2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ELF-1; EPLG6; HEK7-L; LERK-6; LERK6

Description (Vector)

EFNA2 encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm.

Gene ID

1943

Gene Name (Vector)

ephrin A2

Gene Symbol

EFNA2

HGNC ID

HGNC:3222

ORF Size (aa)

642

ORF Size (bp)

642 bp

RefSeq ID

NM_001405

RefSeq Synonyms

NM_001405, BC148727, BC146278,

Species

human

UniGene ID

Hs.532655

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.