human EDNRA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EDNRA.
shAAV-207569
AAV-h-EDNRA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EDNRA (endothelin receptor type A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ET-A; ETA; ETA-R; ETAR; ETRA; hET-AR; MFDA
Description (Vector)
EDNRA encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
Gene ID
1909
Gene Name (Vector)
endothelin receptor type A
Gene Symbol
EDNRA
HGNC ID
HGNC:3179
ORF Size (aa)
1284
ORF Size (bp)
1284 bp
RefSeq ID
NM_001957
RefSeq Synonyms
NM_001957, NM_001256283, NM_001166055, BC022511,
Species
human
UniGene ID
Hs.183713
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.