human EDEM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human EDEM2.
shAAV-207559
AAV-h-EDEM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bA4204.1; C20orf31; C20orf49
Description (Vector)
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 (PubMed 15537790)).(supplied by OMIM, Mar 2008)
Gene ID
55741
Gene Name (Vector)
ER degradation enhancing alpha-mannosidase like protein 2
Gene Symbol
EDEM2
HGNC ID
HGNC:15877
ORF Size (aa)
1737
ORF Size (bp)
1737 bp
RefSeq ID
NM_018217
RefSeq Synonyms
NM_018217, NM_001145025, BC016184, BC001371,
Species
human
UniGene ID
Hs.356273
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.