human EDC4 shRNA silencing AAV

Name 
AAV-h-EDC4-shRNA
Cat No 
shAAV-207556
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EDC4.

shAAV-207556
AAV-h-EDC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EDC4 (enhancer of mRNA decapping 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
autoantigen Ge-1; autoantigen RCD-8; enhancer of mRNA-decapping protein 4; GE1; Ge-1; HEDL5; HEDLS; human enhancer of decapping large subunit; RCD8; RCD-8
Description (eCommerce)
RCD8 has been identified as part of an mRNA decapping complex that includes the hDcp1, and hDcp2 decapping enzyme subunits. RCD8 is important to the functional interaction between hDcp1 and hDcp2 that is essential for regulated mRNA degradation and turnover. RCD8 has also been identified as an autoantigen in human serum.
Gene ID
23644
Gene Name (eCommerce)
enhancer of mRNA decapping 4
Gene Name (Vector)
enhancer of mRNA decapping 4
Gene Symbol
EDC4
HGNC ID
HGNC:17157
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4206
ORF Size (bp)
4206 bp
Protein Name (eCommerce)
Enhancer of mRNA-decapping protein 4
RefSeq ID
NM_014329
RefSeq Synonyms
NM_014329, BC064567, BC043616,
Research Areas
Gene Expression,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
RCD8 has been identified as part of an mRNA decapping complex that includes the hDcp1, and hDcp2 decapping enzyme subunits. RCD8 is important to the functional interaction between hDcp1 and hDcp2 that is essential for regulated mRNA degradation and turnover. RCD8 has also been identified as an autoantigen in human serum.
UniGene ID
Hs.75682
UniProt ID (eCommerce)
Q6P2E9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.