human ECHS1 shRNA silencing AAV

Name 
AAV-h-ECHS1-shRNA
Cat No 
shAAV-207535
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ECHS1.

shAAV-207535
AAV-h-ECHS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ECHS1 (enoyl-CoA hydratase, short chain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ECHS1D; SCEH
Description (Vector)
ECHS1 functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.
Gene ID
1892
Gene Name (Vector)
enoyl-CoA hydratase, short chain 1
Gene Symbol
ECHS1
HGNC ID
HGNC:3151
ORF Size (aa)
873
ORF Size (bp)
873 bp
RefSeq ID
NM_004092
RefSeq Synonyms
NM_004092, BC008906,
Species
human
UniGene ID
Hs.76394

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.