human ECE1 shRNA silencing AAV

Name
AAV-h-ECE1-shRNA

Cat No
shAAV-207525

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ECE1.

shAAV-207525

AAV-h-ECE1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ECE1 (endothelin converting enzyme 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ECE

Description (Vector)

ECE1 is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene ID

1889

Gene Name (Vector)

endothelin converting enzyme 1

Gene Symbol

ECE1

HGNC ID

HGNC:3146

ORF Size (aa)

2313

ORF Size (bp)

2313 bp

RefSeq ID

NM_001397

RefSeq Synonyms

NM_001397, NM_001113349, NM_001113348, NM_001113347, BC126257, BC117256,

Species

human

UniGene ID

Hs.195080

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.