human EBF3 shRNA silencing AAV

Name 
AAV-h-EBF3-shRNA
Cat No 
shAAV-207514
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EBF3.

shAAV-207514
AAV-h-EBF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EBF3 (early B-cell factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COE3; EBF-3; O/E-2; OE-2
Description (Vector)
EBF3 encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.
Gene ID
253738
Gene Name (Vector)
early B-cell factor 3
Gene Symbol
EBF3
HGNC ID
HGNC:19087
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_001005463
RefSeq Synonyms
NM_001005463, BC130479, BC126130,
Species
human
UniGene ID
Hs.591374

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.