human DYRK3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DYRK3.
shAAV-207483
AAV-h-DYRK3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DYRK5; hYAK3-2; RED; REDK
Description (Vector)
DYRK3 product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
8444
Gene Name (Vector)
dual specificity tyrosine phosphorylation regulated kinase 3
Gene Symbol
DYRK3
HGNC ID
HGNC:3094
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_003582
RefSeq Synonyms
NM_003582, NM_001004023, BC015501,
Species
human
UniGene ID
Hs.164267
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.