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human DUX1 shRNA silencing AAV

Name 
AAV-h-DUX1-shRNA
Cat No 
shAAV-207449
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DUX1.

shAAV-207449
AAV-h-DUX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DUX1 (double homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX1, resides within these 3.3-kb repeated elements (Beckers et al., 2001 (PubMed 11245978)). See DUX4 (MIM 606009).(supplied by OMIM, Mar 2008)
Gene ID
26584
Gene Name (Vector)
double homeobox 1
Gene Symbol
DUX1
HGNC ID
HGNC:3079
ORF Size (aa)
513
RefSeq ID
NM_012146
RefSeq Synonyms
NM_012146, BC156917,
Species
human
UniGene ID
Hs.274469

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.