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human DSG4 shRNA silencing AAV

Name 
AAV-h-DSG4-shRNA
Cat No 
shAAV-207354
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DSG4.

shAAV-207354
AAV-h-DSG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DSG4 (desmoglein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDGF13; CDHF13; HYPT6; LAH
Description (Vector)
DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants.
Gene ID
147409
Gene Name (Vector)
desmoglein 4
Gene Symbol
DSG4
HGNC ID
HGNC:21307
ORF Size (aa)
3123
ORF Size (bp)
3123 bp
RefSeq ID
NM_177986
RefSeq Synonyms
NM_177986, NM_001134453, BC132909, BC132907,
Species
human
UniGene ID
Hs.407618

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.