human DPP8 shRNA silencing AAV

Name
AAV-h-DPP8-shRNA

Cat No
shAAV-207296

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DPP8.

shAAV-207296

AAV-h-DPP8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DPP8 (dipeptidyl peptidase 8). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DP8; DPRP-1; DPRP1; MST097; MSTP097; MSTP135; MSTP141

Description (Vector)

DPP8 encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID

54878

Gene Name (Vector)

dipeptidyl peptidase 8

Gene Symbol

DPP8

HGNC ID

HGNC:16490

ORF Size (aa)

2544

ORF Size (bp)

2544 bp

RefSeq ID

NM_017743

RefSeq Synonyms

NM_197961, NM_197960, NM_130434, NM_017743, NM_001320876, NM_001320875, BC030688,

Species

human

UniGene ID

Hs.591106

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.